Italian actress Monica Bellucci and Vincent Cassel are calling it quits and ending their 14-year marriage and are heading toward divorce. They have confirmed that they are “ separating by mutual agreement,” as reported by the Huffington Post.

It follows weeks of speculation about the couple’s increasingly tumultuous relationship.

The couple met on the set of set of Gilles Mimouni’s French-language film called, “The Apartment” in 1996. They were together for three years before marrying in a quiet ceremony in Monaco, on the French Riviera. They have two daughters — Deva, 7, and Leonie, 3.

Both have starred in their share of films with Bellucci, 48, starring in The Matrix Reloaded, Tears of the Son and Mel Gibson’s The Passion of the Christ.

While Cassel is known to American audiences for his work in Black Swan, Eastern Promises, The Messenger, Elizabeth and Ocean’s Twelve and Ocean’s Thirteen. Cassell is hugely popular in his home country of France, where he first leapt into the public imagination in ‘La Haine’ (Hate), a film about delinquents on a troubled Paris housing estate.

The Hollywood beauty told Grazia magazine in April: ‘Marriage, we never know how long it will last…Today, it works, but in a year, I don’t know.’

That same month, Cassel, 46, told Closer magazine: ‘My wife and me are very different animals. This is probably the key to our relationship after 18 years together…We don’t seek other people’s approval.’

The couple had been leading independent lives for several years, keeping their own respective apartments in Paris and Rome.  Cassel also spent a great deal of time alone in Brazil.

The split marks the second marriage failure for Bellucci, a former model, who was with Italian photographer Claudio Basso for four years, before divorcing him in 1994.

The actress is currently away working in Serbia, while Cassel is thought to be in France.